Alphabetical listing of popular business hours in Roanoke:
- 7-Eleven
- Aaron's
- Abuelo's
- Ace Hardware
- Advance Auto Parts
- American Eagle Outfitters
- Anytime Fitness
- Applebee's
- Arby's
- Auntie Anne's
- Avis Rent A Car
- Babies R Us
- Bank Of America
- Barnes & Noble Booksellers
- Batteries Plus
- BB&T
- Bed Bath & Beyond
- Belk
- Beltone Hearing Aid Ctr
- Ben & Jerry's
- Best Buy
- Big Lots
- Blimpie Subs & Salads
- Bojangles' Famous Chicken
- Bruster's Ice Cream
- Buckle
- Budget Rent A Car
- Budget Truck Rental
- Buffalo Wild Wings Grill & Bar
- Burger King
- Burlington Coat Factory
- Carrabba's Italian Grill
- Catherines Plus Sizes
- Cato
- Chase Bank
- Checkers
- Cheddar's Scratch Kitchen
- Chick-Fil-A
- Chuck E Cheese's
- Cici's Pizza
- CITGO
- Cricket Wireless
- Curves
- CVS Pharmacy
- Dairy Queen
- Denny's
- Dick's Sporting Goods
- Dollar General
- Dollar Tree
- Domino's Pizza
- Dunkin Donuts
- Exxon Mobil
- Family Christian Book Store
- Firehouse Subs
- First Citizens Bank
- First National Bank
- Five Guys
- Food Lion
- Game Stop
- Gander Mountain
- Gap
- GNC
- Golden Corral Buffet & Grill
- Good Neighbor Pharmacy
- Great Clips
- Gymboree
- Hallmark
- Hancock Fabrics
- Hardee's
- Health Mart Pharmacy
- Hertz Rent A Car
- H H Gregg Appliances
- Hibbett Sports
- Home Depot
- HoneyBaked Ham
- IHOP
- J C Penney
- Jersey Mike's Subs
- Jiffy Lube
- Jo-Ann Fabrics & Crafts
- Kay Jewelers
- KFC
- Kmart
- Kohl's
- Krispy Kreme Doughnuts
- Lane Bryant
- Lens Crafters
- Limited
- Little Caesars Pizza
- Loft
- Logan's Roadhouse
- Longhorn Steakhouse
- Long John Silver's
- Macy's
- Marshalls
- Mattress Firm
- McAlister's Deli
- McDonald's
- Meineke Car Care Ctr
- Mellow Mushroom
- Michaels Arts & Crafts Store
- Midas Auto Svc Experts
- Miracle-Ear
- Moe's Southwest Grill
- Monro Muffler Brake & Svc
- Murphy
- NAPA Truck Service Center
- O'Charley's
- Office Depot
- Old Navy
- Olive Garden
- O'Reilly Auto Parts
- Outback Steakhouse
- Pacific Sunwear
- Panera Bread
- Papa John's Pizza
- Payless Shoe Source
- Penn Station
- Penske Truck Rental
- PETCO
- Petsmart
- Pier 1 Imports
- Pizza Hut
- Plato's Closet
- PNC Bank
- Popeyes Chicken & Biscuits
- Public Storage
- Quiznos Sub
- Rack Room Shoes
- Radio Shack
- Red Lobster
- Red Robin Gourmet Burgers
- Red Wing Shoe Store
- Ross Dress For Less
- Ruby Tuesday
- Sally Beauty Supply
- Sam's Club
- Sbarro
- Sears Roebuck & Co
- Sherwin-Williams Paints
- Shopping Malls
- Sir Speedy Printing Ctr
- Smart Style Family Hair Salon
- Smokey Bones Bar & Fire Grill
- Smoothie King
- Sonic Drive-In
- Staples
- Starbucks
- Steak 'n Shake
- Stein Mart