Alphabetical listing of popular business hours in Picayune:
- Aaron's
- Ace Hardware
- Advance Auto Parts
- Anytime Fitness
- Applebee's
- Automotive Service Association
- Burger King
- Carquest Auto Parts
- Cato
- Chevron
- Cricket Wireless
- Curves
- CVS Pharmacy
- Dairy Queen
- Dollar General
- Dollar Tree
- Domino's Pizza
- Exxon Mobil
- First National Bank
- Fred's
- Game Stop
- GNC
- Godfather's Pizza
- Hardee's
- Hibbett Sports
- Home Depot
- IHOP
- KFC
- McDonald's
- Murphy