Alphabetical listing of popular business hours in Cape Girardeau:
- Aaron's
- Ace Hardware
- Advance Auto Parts
- ALDI
- American Eagle Outfitters
- Anytime Fitness
- Applebee's
- Arby's
- Bank Of America
- Barnes & Noble Booksellers
- Beef O'Brady's
- Beltone Hearing Aid Ctr
- Best Buy
- Big Lots
- Blimpie Subs & Salads
- Buckle
- Budget Truck Rental
- Buffalo Wild Wings Grill & Bar
- Burger King
- Cato
- Chick-Fil-A
- Cici's Pizza
- Cracker Barrel
- Cricket Wireless
- Culver's
- CVS Pharmacy
- Dairy Queen
- Denny's
- Dollar General
- Dollar Tree
- Domino's Pizza
- Dress Barn
- Dunkin Donuts
- Exxon Mobil
- Fazoli's
- Firehouse Subs
- Game Stop
- GNC
- Golden Corral Buffet & Grill
- Good Neighbor Pharmacy
- Great Clips
- Gymboree
- Hallmark
- Hancock Fabrics
- Hardee's
- Hibbett Sports
- Hobby Lobby
- HoneyBaked Ham
- Huddle House
- IHOP
- J C Penney
- Jimmy John's
- Kay Jewelers
- KFC
- Kmart
- Kohl's
- Lane Bryant
- Lens Crafters
- Little Caesars Pizza
- Logan's Roadhouse
- Long John Silver's
- Macy's
- Marco's Pizza
- Mattress Firm
- Maurice's
- McAlister's Deli
- McDonald's
- Midas Auto Svc Experts
- Miracle-Ear
- NAPA Truck Service Center
- O'Charley's
- Old Navy
- Olive Garden
- O'Reilly Auto Parts
- Outback Steakhouse
- Pacific Sunwear
- Panera Bread
- Papa John's Pizza
- Party City
- Payless Shoe Source
- Penn Station
- Penske Truck Rental
- PETCO
- Pier 1 Imports
- Pizza Hut
- Pizza Inn
- Popeyes Chicken & Biscuits
- Qdoba Mexican Grill
- Quiznos Sub
- Radio Shack
- Red Lobster
- Regions
- Ruby Tuesday
- Sally Beauty Supply
- Sam's Club
- Save-A-Lot
- Schnucks
- Sears Roebuck & Co
- Sherwin-Williams Paints
- Shopping Malls
- Smart Style Family Hair Salon
- Smoothie King
- Sonic Drive-In
- Staples
- Steak 'n Shake
- Subway
- Supercuts
- Taco Bell
- Taco John's
- Target
- Texas Roadhouse
- the Shoe Department
- T J Maxx
- Toys R Us
- Tuesday Morning
- US Bank
- Victoria's Secret
- Walgreens
- Wal-Mart
- Wells Fargo Bank